Aran Singanayagam: search on Z-Library

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1

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

Singanayagam, Aran, Glanville, Nicholas, Girkin, Jason L., Ching, Yee Man, Marcellini, Andrea, Porter, James D., Toussaint, Marie, Walton, Ross P., Finney, Lydia J., Aniscenko, Julia, Zhu, Jie, Trujil

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

2

Risk Factors for Aspiration in Community-acquired Pneumonia: Analysis of a Hospitalized UK Cohort

Taylor, Joanne K., Fleming, Gillian B., Singanayagam, Aran, Hill, Adam T., Chalmers, James D.

Journal:

The American Journal of Medicine

Year:

2013

Language:

english

File:

PDF, 258 KB

english, 2013

3

β 2 -Agonists Enhance Asthma-Relevant Inflammatory Mediators in Human Airway Epithelial Cells

Ritchie, Andrew I., Singanayagam, Aran, Wiater, Ezra, Edwards, Michael R., Montminy, Marc, Johnston, Sebastian L.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2018

Language:

english

File:

PDF, 587 KB

english, 2018

4

In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist /β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients

Milara, Javier, Contreras, Sonia, de Diego, Alfredo, Calbet, Marta, Aparici, Mònica, Morcillo, Esteban, Miralpeix, Montserrat, Cortijo, Julio, Singanayagam, Aran

Journal:

Year:

2019

Language:

english

File:

PDF, 3.02 MB

english, 2019

5

Review of the British Thoracic Society Winter Meeting 2018, 5–7 December 2018, London, UK

Goodwin, Amanda T, Singanayagam, Aran, Jenkins, Gisli

Journal:

Year:

2019

Language:

english

File:

PDF, 311 KB

english, 2019

6

LONG TERM IMPACT OF INHALED CORTICOSTEROID USE IN ASTHMA AND COPD: REVIEW OF MECHANISMS THAT UNDERLIE RISKS

Singanayagam, Aran, Johnston, Sebastian L.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2020

Language:

english

File:

PDF, 3.87 MB

english, 2020

7

Repurposing Existing Drugs for the Treatment of COVID-19

Farne, Hugo, Kumar, Kartik, Ritchie, Andrew I, Finney, Lydia J, Johnston, Sebastian L, Singanayagam, Aran

Journal:

Annals of the American Thoracic Society

Year:

2020

File:

PDF, 292 KB

2020

8

Admission D-dimer Can Identify Low-Risk Patients With Community-Acquired Pneumonia

James D. Chalmers, Aran Singanayagam, Caroline Scally, Adam T. Hill

Journal:

Annals of Emergency Medicine

Year:

2009

Language:

english

File:

PDF, 336 KB

english, 2009

9

Severity assessment tools to guide ICU admission in community-acquired pneumonia: systematic review and meta-analysis

James D. Chalmers, Pallavi Mandal, Aran Singanayagam, Ahsan R. Akram, Gourab Choudhury, Philip M. Short, Adam T. Hill

Journal:

Intensive Care Medicine

Year:

2011

Language:

english

File:

PDF, 455 KB

english, 2011

10

Factors associated with severe illness in pandemic 2009 influenza a (H1N1) infection: Implications for triage in primary and secondary care

Anika Singanayagam, Aran Singanayagam, Victoria Wood, James D. Chalmers

Journal:

Journal of Infection

Year:

2011

Language:

english

File:

PDF, 330 KB

english, 2011

11

C-Reactive Protein Is an Independent Predictor of Severity in Community-acquired Pneumonia

James D. Chalmers, Aran Singanayagam, Adam T. Hill

Journal:

The American Journal of Medicine

Year:

2008

Language:

english

File:

PDF, 107 KB

english, 2008

12

The Reply

James D. Chalmers, Aran Singanayagam, Adam T. Hill

Journal:

The American Journal of Medicine

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

13

Prior Statin Use Is Associated with Improved Outcomes in Community-acquired Pneumonia

James D. Chalmers, Aran Singanayagam, Maeve P. Murray, Adam T. Hill

Journal:

The American Journal of Medicine

Year:

2008

Language:

english

File:

PDF, 149 KB

english, 2008

14

The Reply

James D. Chalmers, Aran Singanayagam, Adam T. Hill

Journal:

The American Journal of Medicine

Year:

2009

Language:

english

File:

PDF, 75 KB

english, 2009

15

Right ventricular dilation on CT pulmonary angiogram independently predicts mortality in pulmonary embolism

Aran Singanayagam, James D. Chalmers, Caroline Scally, Ahsan R. Akram, Mudher Z. Al-Khairalla, Leah Leitch, Louise E. Hill, Adam T. Hill

Journal:

Respiratory Medicine

Year:

2010

Language:

english

File:

PDF, 183 KB

english, 2010

16

Post-bronchoscopy sputum: Improving the diagnostic yield in smear negative pulmonary TB

Peter M. George, Meera Mehta, Jaideep Dhariwal, Aran Singanayagam, Claire E. Raphael, Mohammad Salmasi, David W. Connell, Philip Molyneaux, Melissa Wickremasinghe, Annette Jepson, Onn Min Kon

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 416 KB

english, 2011

17

Budesonide and risk of pneumonia

Aran Singanayagam, James D Chalmers

Journal:

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

18

Viruses exacerbating chronic pulmonary disease: the role of immune modulation

Aran Singanayagam, Priya V Joshi, Patrick Mallia, Sebastian L Johnston

Journal:

Year:

2012

Language:

english

File:

PDF, 411 KB

english, 2012

19

Role Of Interleukine-33 In Rhinovirus-Induced Allergic Asthma Exacerbation

Toussaint, Marie, Singanayagam, Aran, Johnston, Sebastian L., Bartlett, Nathan

Journal:

Journal of Allergy and Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 38 KB

english, 2014

20

Severity assessment scores to guide empirical use of antibiotics in community acquired pneumonia

Singanayagam, Aran, Chalmers, James D

Journal:

The Lancet Respiratory Medicine

Year:

2013

Language:

english

File:

PDF, 476 KB

english, 2013

21

Predictors of Mortality in Hospitalized Adults with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. A Systematic Review and Meta-analysis

Singanayagam, Aran, Schembri, Stuart, Chalmers, James D.

Journal:

Annals of the American Thoracic Society

Year:

2013

Language:

english

File:

PDF, 577 KB

english, 2013

22

Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease

Finney, Lydia, Berry, Matthew, Singanayagam, Aran, Elkin, Sarah L, Johnston, Sebastian L, Mallia, Patrick

Journal:

The Lancet Respiratory Medicine

Year:

2014

Language:

english

File:

PDF, 492 KB

english, 2014

23

Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy?

Harrison, Michelle T, Short, Philip, Williamson, Peter A, Singanayagam, Aran, Chalmers, James D, Schembri, Stuart

Journal:

Year:

2014

Language:

english

File:

PDF, 418 KB

english, 2014

24

Exhaled breath acetone for therapeutic monitoring in pneumonia using selected ion flow tube mass spectrometry (SIFT-MS)

Huang, Juzheng, Kumar, Sacheen, Singanayagam, Aran, George, Peter M., Kon, Onn Min, Takata, Masao, Hanna, George B.

Journal:

Analytical Methods

Year:

2013

Language:

english

File:

PDF, 365 KB

english, 2013

25

A Comparison between Two Strategies for Monitoring Hepatic Function during Antituberculous Therapy

Singanayagam, Aran, Sridhar, Saranya, Dhariwal, Jaideep, Abdel-Aziz, Dalia, Munro, Kerry, Connell, David W., George, Peter M., Molyneaux, Philip L., Cooke, Graham S., Burroughs, Andrew K., Lalvani, Aj

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 137 KB

english, 2012

26

Effect of fluticasone propionate on virus-induced airways inflammation and anti-viral immune responses in mice

Singanayagam, Aran, Glanville, Nicholas, Bartlett, Nathan, Johnston, Sebastian

Journal:

Year:

2015

Language:

english

File:

PDF, 60 KB

english, 2015

27

Predicting the Need for Mechanical Ventilation and/or Inotropic Support for Young Adults Admitted to the Hospital with Community‐Acquired Pneumonia

Chalmers, James D., Singanayagam, Aran, Hill, Adam T.

Journal:

Clinical Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 215 KB

english, 2008

28

A short-term mouse model that reproduces the immunopathological features of rhinovirus-induced exacerbation of COPD

Singanayagam, Aran, Glanville, Nicholas, Walton, Ross P., Aniscenko, Julia, Pearson, Rebecca M., Pinkerton, James W., Horvat, Jay C., Hansbro, Philip M., Bartlett, Nathan W., Johnston, Sebastian L.

Journal:

Clinical Science

Year:

2015

Language:

english

File:

PDF, 1.71 MB

english, 2015

29

Antibiotic treatment in exacerbations of chronic obstructive pulmonary disease: recent trial results

Manalan, Kavina, Rashid, Taslima, Singanayagam, Aran

Journal:

Clinical Investigation

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

30

Performance of Xpert MTB/RIF in the Diagnosis of Tuberculous Mediastinal Lymphadenopathy by Endobronchial Ultrasound

Dhasmana, Devesh J., Ross, Clare, Bradley, Clare J., Connell, David W., George, Peter M., Singanayagam, Aran, Jepson, Annette, Craig, Clare, Wright, Corrina, Molyneaux, Philip L., Wickremasinghe, Meli

Journal:

Annals of the American Thoracic Society

Year:

2014

Language:

english

File:

PDF, 482 KB

english, 2014

31

Incidence and Prognostic Implications of Acute Kidney Injury on Admission in Patients With Community-Acquired Pneumonia

Akram, Ahsan R., Singanayagam, Aran, Choudhury, Gourab, Mandal, Pallavi, Chalmers, James D., Hill, Adam T.

Journal:

Year:

2010

Language:

english

File:

PDF, 123 KB

english, 2010

32

Reply: Adaptation and Antituberculosis Drug–induced Liver Injury

Singanayagam, Aran, Burroughs, Andrew K., Min Kon, Onn, Wickremasinghe, Melissa

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2012

Language:

english

File:

PDF, 128 KB

english, 2012

33

Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia

Chalmers, James D., Akram, Ahsan R., Singanayagam, Aran, Wilcox, Mark H., Hill, Adam T.

Journal:

Journal of Infection

Year:

2016

Language:

english

File:

PDF, 500 KB

english, 2016

34

Juniors’ voice at the ERS International Congress, Amsterdam 2015

Polverino, Francesca, Longhini, Federico, Vanaudenaerde, Bart, Bikov, Andras, Aamli, Ane, Singanayagam, Aran, Kahn, Nicolas, Boots, Agnes, Skoczynski, Szymon

Journal:

Year:

2015

Language:

english

File:

PDF, 71 KB

english, 2015

35

Early Career Members at the ERS International Congress London 2016

Bos, Lieuwe D., Bartel, Sabine, Ojanguren Arranz, Inigo, Kahn, Nicolas C., Mathioudakis, Alexander G., Flood, Emma, Petrarca, Laura, Singanayagam, Aran, Hardavella, Georgia

Journal:

Year:

2016

Language:

english

File:

PDF, 81 KB

english, 2016

36

Oral versus intravenous clarithromycin in moderate to severe community-acquired pneumonia: an observational study

Rae, Nikolas, Singanayagam, Aran, Schembri, Stuart, Chalmers, James D.

Journal:

pneumonia A Peer Reviewed Open Access Journal

Year:

2017

Language:

english

File:

PDF, 465 KB

english, 2017

37

Role of microbiome in the pathophysiology and disease course of asthma

Singanayagam, Aran, Ritchie, Andrew I., Johnston, Sebastian L.

Journal:

Current Opinion in Pulmonary Medicine

Year:

2017

Language:

english

File:

PDF, 234 KB

english, 2017

38

Hospitalized AECOPD Patients Not Treated With Antibiotic Have Higher Rates of 1-Year Pneumonia Related Hospitalization

Reyes, Luis, Restrepo, Marcos, Sibila, Oriol, Schembri, Stuart, Williamson, Peter, Short, Philip, Akram, Ahsan, Singanayagam, Aran, Chalmers, James

Journal:

Year:

2014

Language:

english

File:

PDF, 17 KB

english, 2014

39

Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease

Mallia, Patrick, Webber, Jessica, Gill, Simren K., Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria Adelaide, Finney, Lydia, Bakhsoliani, Eteri, Farne, Hugo, Singanayagam, Aran, Footitt, Joseph, Hewi

Journal:

Journal of Allergy and Clinical Immunology

Year:

2018

Language:

english

File:

PDF, 1.58 MB

english, 2018

40

Folate deficiency presenting as pyrexia: a case report

Singanayagam, Aran, Gange, Nisal, Singanayagam, Anika, Jones, Hywel

Journal:

Year:

2008

Language:

english

File:

PDF, 379 KB

english, 2008

41

Review of the British Thoracic Society Winter Meeting 2017, 6–8 December 2017, London, UK

Singanayagam, Aran, Woodcock, Hannah V, Molyneaux, Philip L, Jenkins, Gisli

Journal:

Year:

2018

Language:

english

File:

PDF, 213 KB

english, 2018

42

Atopic asthmatic immune phenotypes associated with airway microbiota and airway obstruction

Turturice, Benjamin A., McGee, Halvor S., Oliver, Brian, Baraket, Melissa, Nguyen, Brian T., Ascoli, Christian, Ranjan, Ravi, Rani, Asha, Perkins, David L., Finn, Patricia W., Singanayagam, Aran

Journal:

Year:

2017

Language:

english

File:

PDF, 2.55 MB

english, 2017

43

Chronic obstructive pulmonary disease candidate gene prioritization based on metabolic networks and functional information

Wang, Xinyan, Li, Wan, Zhang, Yihua, Feng, Yuyan, Zhao, Xilei, He, Yuehan, Zhang, Jun, Chen, Lina, Singanayagam, Aran

Journal:

Year:

2017

Language:

english

File:

PDF, 3.68 MB

english, 2017

44

Evidence of superficial knowledge regarding antibiotics and their use: Results of two cross-sectional surveys in an urban informal settlement in Kenya

Omulo, Sylvia, Thumbi, Samuel M., Lockwood, Svetlana, Verani, Jennifer R., Bigogo, Godfrey, Masyongo, Geoffrey, Call, Douglas R., Singanayagam, Aran

Journal:

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

45

Lung microbiology and exacerbations in COPD

Johnston, Sebastian, Molyneaux, Philip, Singanayagam, Aran, Beasley,, Joshi,, Mallia, Patrick

Journal:

International Journal of Chronic Obstructive Pulmonary Disease

Year:

2012

Language:

english

File:

PDF, 452 KB

english, 2012

46

Severe Disseminated Infection with Emerging Lineage of Methicillin-Sensitive Staphylococcus aureus

Jewell, Paul, Dixon, Luke, Singanayagam, Aran, Ghani, Rohma, Wong, Ernie, Coleman, Meg, Pichon, Bruno, Kearns, Angela, Russell, Georgina, Hatcher, James

Journal:

Emerging Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 490 KB

english, 2018

47

Respiratory infection: insights from Assembly 10 of the European Respiratory Society 2017 Annual Congress

Garcia-Basteiro, Alberto L., Wong, Ernie, Van Oort, Pouline M., Cilloniz, Catia, Migliori, Giovanni Battista, Singanayagam, Aran

Journal:

Journal of Thoracic Disease

Year:

2017

Language:

english

File:

PDF, 151 KB

english, 2017

48

Respiratory infection: insights from assembly 10 of the European Respiratory Society 2018 Annual Congress

Calarasu, Cristina, Singanayagam, Aran

Journal:

Journal of Thoracic Disease

Year:

2018

Language:

english

File:

PDF, 103 KB

english, 2018

49

Inflammation and infections in unreported chronic obstructive pulmonary disease exacerbations

Calderazzo, Maria Adelaide, Trujillo-Torralbo, Maria-Belen, Finney, Lydia Joanne, Singanayagam, Aran, Bakhsoliani, Eteri, Padmanaban, Vijay, Kebadze, Tatiana, Aniscenko, Julia, Elkin, Sarah L, Johnsto

Journal:

International Journal of Chronic Obstructive Pulmonary Disease

Year:

2019

Language:

english

File:

PDF, 383 KB

english, 2019

50

Anti-viral immunity is impaired in COPD patients with frequent exacerbations

Singanayagam, Aran, Loo, Su-Ling, Calderazzo, Maria Adelaide, Finney, Lydia J., Trujillo Torralbo, Maria-Belen, Bakhsoliani, Eteri, Girkin, Jason, Veerati, Punnam Chander, Pathinayake, Prabuddha S, Ni

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2019

Language:

english

File:

PDF, 691 KB

english, 2019